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7 min read
Sam North
As global policies change, the ever-increasing body of research into the therapeutic possibilities of medical cannabis has led to a deeper understanding of the complex chemical makeup of this plant.
While cannabinoids (THC and CBD) remain the "main players" in the medicinal properties of cannabis, the emerging evidence is showing that terpenes - the aromatic compounds responsible for the distinct smell of different cultivars - also play a crucial role in its clinical efficacy.
Cannabis sativa L. cultivars have been shown to produce up to four hundred different terpenes, but most of these come in exceedingly small concentrations. That said, there are a range of terpenes that come in much higher levels, and this includes today's hero - linalool.
Whether you realise it or not, you actually already know linalool.
Terpenes are the organic compounds that offer up all the lovely aromas we associate with nature, and linalool is one of the most common. It's not just cannabis plants that produce terpenes. They are widespread throughout the plant kingdom, and you'll find linalool in a bunch of well-loved greenery.
Along with cannabis plants, linalool is produced in high concentrations in lavender, mint, sweet basil, cinnamon, rosewood, and coriander - to name just a few. It has a distinct floral scent that is most often described as delicate, sweet, and citrusy - with a hint of spice. It's soothing and calming, with a subtly sedative effect - which is why it has been used for centuries in aromatherapy.
At this point, it is important to note that research into the therapeutic applications of linalool is ongoing, but the results so far are very promising. Linalool has been shown to have a wide range of potential health benefits, including anti-inflammatory, pain-relieving, and antibacterial properties, to name just a few.
Thanks to the abundance of linalool throughout the natural world, it has been extensively studied.
Linalool has demonstrated potential in:
As research continues, we expect to see increased applications for linalool in the treatment of various health issues.
Before we dive into the specifics of linalool, let's take a quick look at how terpenes, in general, affect the therapeutic potential of medical cannabis.
Terpenes may act synergistically with cannabinoids to enhance their effects, and some studies suggest that certain combinations can produce enhanced therapeutic effects compared to using cannabinoids alone. This is known as the "entourage effect".
This widely accepted theory first emerged in 1998. Professors Raphael Mechoulam and Shimon Ben-Shabat from the Hebrew University in Jerusalem suggested that cannabinoids and terpenes work together to enhance the medicinal properties of cannabis.
This theory has been supported by various studies, including a 2011 study published in the British Journal of Pharmacology, which showed that combining THC with other cannabinoids and terpenoids resulted in more significant pain relief than using THC alone.
Essentially, the theory posits that combining phytocannabinoids (THC, CBD, CBN, etc.) and terpenes (linalool, limonene, myrcene, humulene, beta-caryophyllene) may offer enhanced therapeutic benefits. However, this is still just a theory, and more research is needed to confirm these results.
There are a few options that UK patients can speak to their prescribing specialist about if they are looking for a high concentration of linalool:
It sure is.
Linalool is a common additive in skincare products, perfumes and cosmetics, and household cleaning products. It is also used as a flavouring agent in food and beverages.
Although linalool application can come with certain side effects, the fact that the concentrations of linalool in medical cannabis oil and flower options are relatively low when compared to essential oils or other concentrated forms reduces the risks.
Some of the side effects of linalool may include:
As with all cannabis-based therapeutic options, you should always look to titrate (start low, go slow) your dose and use the smallest effective amount.
Speaking to your prescribing specialist before adding any new product or substance to your medical treatment plan is always important. They will be able to advise you on potential interactions or risks based on your specific health needs.
Linalool is one of the 20,000 or so naturally occurring terpenes that have been isolated so far, and one of around 400 produced by Cannabis sativa L. cultivars. It is known for its calming and stress-reducing effects, as well as its potential to act as an antidepressant, anti-inflammatory, and antibacterial agent. In the context of cannabis, linalool is believed to work synergistically with cannabinoids to enhance therapeutic benefits.
Yes, linalool has long been applied for therapeutic purposes through both aromatherapy and topical applications. However, it is essential to discuss incorporating linalool into your medical treatment plan with your prescribing specialist before doing so - especially if you are interested in taking it in combination with medical cannabis.
The vaporisation temperature of linalool ranges between 388-438°F (198-226°C), depending on the source. This means that it can be easily activated through a vaporiser, with the vapour then being inhaled.
With so many countries now legalising medical cannabis comes increased research funding and improved plans to investigate the therapeutic potential of terpenes like linalool. And the more we know, the more we can customise treatment plans to suit patients' individual needs.
Linalool is one of the most abundant and well-studied terpenes in cannabis and has shown promising results in a bunch of studies. We are excited to see where further research take us, and we will keep you posted when new information becomes available!
If you have any further questions about linalool or other terpenes, feel free to reach out to us or check out our extensive education and blog sections. And don't forget to follow us on Instagram and LinkedIn for everything medical cannabis and Releaf-related.
It is important to seek medical advice before starting any new treatments. The patient advisors at Releaf are available to provide expert advice and support. Alternatively, click here to book a consultation with one of our specialist doctors.
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Am I eligible?Sam North, a seasoned writer with over five years' experience and expertise in medicinal cannabis, brings clarity to complex concepts, focusing on education and informed use.
Our articles are written by experts and reviewed by medical professionals or compliance specialists. Adhering to stringent sourcing guidelines, we reference peer-reviewed studies and scholarly research. View our editorial policy.
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